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horos news

Be up to date! Have a look at our most recent news, and if you want, you can also check the library for 

STAYS ABROAD, PROGRESS-REPORTS & CONGRESSES.

HOROS is on a roll
Date: 2018-09-19   Filed under: News

Thomas Orasch was the next HOROS student who finished successfully his PhD. Since October 2014 he was working in the lab of Univ.-Prof. Mag. Dr. rer. nat Hubertus Haas and investigated the siderophore mediated diagnosis of fungal infections. His main goals were the analysis of the potential of siderophores as specific biomarkers for Aspergillus and the role of leucine biosynthesis in the virulence and as antifungal drug target. Thomas went 5 months abroad to the Department of Molecular and applied Microbiology at the Hans-Knöll-Institute in Jena. At the lab of Dr. Peter Hortschansky he investigated the interaction of proteins with DNA binding domains, which completed his thesis. On the 13th of September he defended his thesis in front of his examiners: Univ. Prof. Mag. Dr. Susanne Zeilinger-Migsich, Prof. Dr. Ilse Denise Jacobsen and Univ.-Prof. Mag. Dr. rer. nat. Stefan Grässle.

HOROS wishes Thomas all the best for his PostDoc in Jena!

Group

HOROS Abroad – Sneha: “Greetings from an exceptionally sunny Copenhagen”
Date: 2018-08-30   Filed under: News

As a HOROS associate student, I got the opportunity to gain research experience in Prof. Peter Garred’s Laboratory of Molecular Medicine at the Department of Clinical Immunology, Rigshospitalet, University of Copenhagen. His group works on understanding the structure and molecular genetics of the complement system. I started my work in his lab in the mid of April and focused mainly on the effect of Shiga toxin on the intracellular complement profile of the human proximal renal tubular epithelial cells, HK-2, which compliments my PhD project in Innsbruck, titled “Interaction of EHEC virulence factor Shiga toxin with the innate immune system”. In particular, the aim of this study was to investigate the role of complement, with special emphasis on the expression of the pivotal complement proteins of the alternative pathway, in the renal epithelial cell line HK-2 and its further implications upon stimulation with Stx2a.
The work culture in Copenhagen and from what I learnt, in Denmark, in general, is quite relaxed and cosmopolitan. My colleagues were extremely warm and welcoming. This being an exceptionally sunny summer in Copenhagen, we spent a lot of time in the sun having weekly cakes, Danish pastries and ice cream “work meetings”, a tradition of the lab. The same fashion extended on the streets with large number of people sitting by the canals or riding bikes by the famous lakes of Copenhagen, basking in the sun in what is known as one of the most bike-friendly cities in the word. Street parties, in numerous tiny wine parlours, cafes and eateries with all types of cuisines, Copenhagen seemed like a worldly cultural city.

Personally, the experience, both work wise and living wise, has been extremely valuable to me. I am thankful to HOROS for giving me this wonderful experience.

Amalienborg Palace, the royal house

Canals of Copenhagen

Christiana

Lakes of Copenhagen

Sakura cherry blossom

The famous Nyhavn

The Queen's boat

One after the other
Date: 2018-08-19   Filed under: News

Stefanie Dichtl started her PhD in October 2014 in the lab of Univ.-Prof. Dr. med. Günter Weiss and worked on the regulation of Dopamine of iron homeostasis and innate immune responses of macrophages to Salmonella infection. During that time, she investigated the effects of catecholamines on the regulation of iron in wild type and lipocalin-2 knockout bone marrow derived macrophages. Steffi had the chance to go abroad for six months and work in the lab of Dr. Peter Murray at the Max-Planck Institute of Biochemistry in Munich. During her stay, she could use already acquired knowledge and learn new methods. On the 8th of August she defended her thesis excellent in front of her examiners Univ.-Prof. Mag. Dr. rer. nat. Hubertus Haas and Univ.-Prof. Mag. rer. nat. Dr. phil. Dietmar Fuchs.

Steffi all the best for your future in Munich from all HOROS!

HOROS Abroad - Carina: Three month in the German metropolis BERLIN
Date: 2018-08-03   Filed under: News

Through the PhD program HOROS I had the great opportunity to go three month abroad to join a world-renowned institute called ‘Deutsches Rheuma-Forschungszentrum’ in Berlin situated at the Charitè under the direction of Andreas Radbruch. There I joined the group of Anja Hauser and Raluca Niesner, which is focusing on advanced intra vital and in vivo microscopy to visualize and quantify immune dynamic processes of cell subsets in the living organism.

At the DRFZ, I’m the first one to work with the light sheet fluorescence microscope visualizing murine myeloid cell subsets within cleared bone tissues in 3D. Due to age-related changes of the efficiency of our immune system a reduced defensive and phagocytic capability regarding macrophages was already observed. Different populations of macrophages are responsible for several important functions in bone regeneration, which gets disturbed during aging. The aim of my project is to characterize and quantify macrophage subsets in young and old mice and compare the density of these cells between different cohorts. Furthermore, we will visualize the spatial localization of adipocytes and possible interactions with macrophages within the bone tissue as well.

I’m currently living in the friendly and trendy district, Kreuzberg. I have learned that Berlin is not only one big city; it consists of little different villages within a city and every district has its charm and mentality. One favorite part of the day is riding my bike to work, because I’m passing all the great sightseeing places early in the morning when tourists are still sleeping. Berlin is a city with thousands of different activities and sightseeing spots that you can do after work. I’m one of the lucky persons who can experience Berlin with one of the best summers of the last years. But it is hard to find a lake or pool to cool down that is not overloaded with people. Since I’m here I’m testing all the different bouldering gyms Berlin has to offer, so I won’t get homesick.

Within these three month I have extended my knowledge in my field of research as well as in others like physics. With this really short summary of three month I’m grateful to have had this great opportunity and I will definitely not forget the friends that I made and the time that I had in Berlin.

DRFZ building

On my way to work passing the Reichstag and the Kanzlerviertel

Some of my lab colleagues at the DRFZ after a fire alarm exercise

‘Ride for silence’ event with friends and work colleagues

After work beach volleyball session in Berlin Mitte. Sporty lab colleagues!

horos news

Be up to date! Have a look at our most recent news, and if you want, you can also check the library for 

STAYS ABROAD, PROGRESS-REPORTS & CONGRESSES.



HOROS is on a roll
Date: 2018-09-19   Filed under: News

Thomas Orasch was the next HOROS student who finished successfully his PhD. Since October 2014 he was working in the lab of Univ.-Prof. Mag. Dr. rer. nat Hubertus Haas and investigated the siderophore mediated diagnosis of fungal infections. His main goals were the analysis of the potential of siderophores as specific biomarkers for Aspergillus and the role of leucine biosynthesis in the virulence and as antifungal drug target. Thomas went 5 months abroad to the Department of Molecular and applied Microbiology at the Hans-Knöll-Institute in Jena. At the lab of Dr. Peter Hortschansky he investigated the interaction of proteins with DNA binding domains, which completed his thesis. On the 13th of September he defended his thesis in front of his examiners: Univ. Prof. Mag. Dr. Susanne Zeilinger-Migsich, Prof. Dr. Ilse Denise Jacobsen and Univ.-Prof. Mag. Dr. rer. nat. Stefan Grässle.

HOROS wishes Thomas all the best for his PostDoc in Jena!

HOROS Abroad – Sneha: “Greetings from an exceptionally sunny Copenhagen”
Date: 2018-08-30   Filed under: News

As a HOROS associate student, I got the opportunity to gain research experience in Prof. Peter Garred’s Laboratory of Molecular Medicine at the Department of Clinical Immunology, Rigshospitalet, University of Copenhagen. His group works on understanding the structure and molecular genetics of the complement system. I started my work in his lab in the mid of April and focused mainly on the effect of Shiga toxin on the intracellular complement profile of the human proximal renal tubular epithelial cells, HK-2, which compliments my PhD project in Innsbruck, titled “Interaction of EHEC virulence factor Shiga toxin with the innate immune system”. In particular, the aim of this study was to investigate the role of complement, with special emphasis on the expression of the pivotal complement proteins of the alternative pathway, in the renal epithelial cell line HK-2 and its further implications upon stimulation with Stx2a.
The work culture in Copenhagen and from what I learnt, in Denmark, in general, is quite relaxed and cosmopolitan. My colleagues were extremely warm and welcoming. This being an exceptionally sunny summer in Copenhagen, we spent a lot of time in the sun having weekly cakes, Danish pastries and ice cream “work meetings”, a tradition of the lab. The same fashion extended on the streets with large number of people sitting by the canals or riding bikes by the famous lakes of Copenhagen, basking in the sun in what is known as one of the most bike-friendly cities in the word. Street parties, in numerous tiny wine parlours, cafes and eateries with all types of cuisines, Copenhagen seemed like a worldly cultural city.

Personally, the experience, both work wise and living wise, has been extremely valuable to me. I am thankful to HOROS for giving me this wonderful experience.

One after the other
Date: 2018-08-19   Filed under: News

Stefanie Dichtl started her PhD in October 2014 in the lab of Univ.-Prof. Dr. med. Günter Weiss and worked on the regulation of Dopamine of iron homeostasis and innate immune responses of macrophages to Salmonella infection. During that time, she investigated the effects of catecholamines on the regulation of iron in wild type and lipocalin-2 knockout bone marrow derived macrophages. Steffi had the chance to go abroad for six months and work in the lab of Dr. Peter Murray at the Max-Planck Institute of Biochemistry in Munich. During her stay, she could use already acquired knowledge and learn new methods. On the 8th of August she defended her thesis excellent in front of her examiners Univ.-Prof. Mag. Dr. rer. nat. Hubertus Haas and Univ.-Prof. Mag. rer. nat. Dr. phil. Dietmar Fuchs.

Steffi all the best for your future in Munich from all HOROS!



HOROS Abroad - Carina: Three month in the German metropolis BERLIN
Date: 2018-08-03   Filed under: News

Through the PhD program HOROS I had the great opportunity to go three month abroad to join a world-renowned institute called ‘Deutsches Rheuma-Forschungszentrum’ in Berlin situated at the Charitè under the direction of Andreas Radbruch. There I joined the group of Anja Hauser and Raluca Niesner, which is focusing on advanced intra vital and in vivo microscopy to visualize and quantify immune dynamic processes of cell subsets in the living organism.

At the DRFZ, I’m the first one to work with the light sheet fluorescence microscope visualizing murine myeloid cell subsets within cleared bone tissues in 3D. Due to age-related changes of the efficiency of our immune system a reduced defensive and phagocytic capability regarding macrophages was already observed. Different populations of macrophages are responsible for several important functions in bone regeneration, which gets disturbed during aging. The aim of my project is to characterize and quantify macrophage subsets in young and old mice and compare the density of these cells between different cohorts. Furthermore, we will visualize the spatial localization of adipocytes and possible interactions with macrophages within the bone tissue as well.

I’m currently living in the friendly and trendy district, Kreuzberg. I have learned that Berlin is not only one big city; it consists of little different villages within a city and every district has its charm and mentality. One favorite part of the day is riding my bike to work, because I’m passing all the great sightseeing places early in the morning when tourists are still sleeping. Berlin is a city with thousands of different activities and sightseeing spots that you can do after work. I’m one of the lucky persons who can experience Berlin with one of the best summers of the last years. But it is hard to find a lake or pool to cool down that is not overloaded with people. Since I’m here I’m testing all the different bouldering gyms Berlin has to offer, so I won’t get homesick.

Within these three month I have extended my knowledge in my field of research as well as in others like physics. With this really short summary of three month I’m grateful to have had this great opportunity and I will definitely not forget the friends that I made and the time that I had in Berlin.

We did it again - third HOROS alumni
Date: 2018-07-18   Filed under: News

More and more students finish their studies - this time it was Hemalata Deshmukh (Priya), who defended her PhD thesis on the 12th of July in front of a huge audience. Priya started with her project as one of the first HOROS students in autumn 2014. Her thesis investigated the relevance of platelets and complement for the pathogenesis of invasive fungal infections. She did very well in presenting her results. We wish you also the best for your future, Priya!





contact

PROGRAMME SPEAKER

Reinhard Würzner, M.D., Ph.D.
Schöpfstraße 41
A-6020 Innsbruck

horos@i-med.ac.at

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